“Hot cross bun” sign in a patient with parkinsonism secondary to presumed vasculitis Journal


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The "hot cross bun" sign is characterized by cross-shaped T2 signal hyperintensity within the pons and has been said to be specific although not pathognomonic for multiple system atrophy (MSA). 1 Case 1 is a 60-year-old woman who presented with progressive spasticity, limb ataxia, and urinary incontinence of 3 Undefined control sequence \ ( Unde.


Figure 1 from The hot cross bun sign. Semantic Scholar

Objectives: The "hot cross bun sign" (HCBs) on magnetic resonance imaging (MRI) has been initially considered specific for multiple system atrophy with cerebellar features. However, a number of other conditions have since been described, which may be associated with this imaging sign.


MSA Hot Cross Bun sign 2 with arrow

Changes are mostly infratentorial, 4 and include the typical hyperintense hot cross bun sign in the pons and other anomalies, such as putamen atrophy, putamen hypointensity and hyperintense putaminal rim. 2-5 The hot cross bun sign is the result of the degeneration of pontine neurons and transverse pontocerebellar fibres.


Hot Cross Bun Sign. Head T2W MRI though the pons showing a hyperintense... Download Scientific

The "hot cross bun sign" (HCBs) on magnetic resonance imaging (MRI) has been initially considered specific for multiple system atrophy with cerebellar features. However, a number of other conditions have since been described, which may be associated with this imaging sign.


Hotcross bun sign of multiple system atrophy Image

The hot cross bun" sign is characterized by cruciform T2 signal hyperintensity within the pons and has been said to be specific although not pathognomonic for multiple system atrophy (MSA). Pontocerebellar degeneration results in lateral as well as longitudinal pontine fibers becoming evident as high signal on T2, manifesting as "hot cross bun.


“Hot cross bun” sign in two patients with multiple system atrophycerebellar Neurology

Brain MRI disclosed the "hot cross bun" sign typical of multiple system atrophy (MSA) ( figure ). 1,2 This sign is probably related to degeneration of transverse pontocerebellar fibers, whereas the hyperintense rim bordering the putamina has been associated with neuronal loss, reactive microgliosis, and astrogliosis. 2 Glial cytoplasmic inclusio.


“Hot cross bun” sign in a patient with parkinsonism secondary to presumed vasculitis Journal

pons ( hot cross bun sign in MSA-C) middle cerebellar peduncles cerebellum abnormal putaminal signal (in MSA-P) 5: reduced GRE and T2 signal relative to the globus pallidus and the red nucleus abnormally high T2 linear rim surrounding the putamen ( putaminal rim sign ) seen at 1.5 T (this is normal at 3 T) 7 (see case 3) disproportionate atrophy


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The "hot cross bun" (HCB) sign, a cruciform hyperintensity in the pons on magnetic resonance imaging (MRI), has gradually been identified as a typical finding in multiple system atrophy, cerebellar-type (MSA-C).


Hotcross bun sign in multiple system atrophy Eurorad

Conventional magnetic resonance imaging is frequently used in the diagnosis of MSA, and "hot cross bun" sign (HCBs) is widely accepted to be a valuable sign for the diagnosis of MSA 6,7,8,9,10.


Axial T2weighted MR image of the brain showed the 'hot cross bun sign'... Download Scientific

Hot cross bun sign is seen in the pons in a Multiple system atrophy (MSA) patient, the sign has also seen with other neurodegenerative diseases such as spinocerebellar atrophy and parkinsonism. In appropriate clinical setting, detection of these changes is useful to confirm the diagnosis of MSA. Related Radiopaedia articles


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The Hot Cross Bun Sign: A Journey Across Etiologies. The Hot Cross Bun Sign: A Journey Across Etiologies Mov Disord Clin Pract. 2022 Oct 21;9(8):1018-1020. doi: 10.1002/mdc3.13596. eCollection 2022 Nov. Authors Shweta Prasad 1 , Malco Rossi 2 3 Affiliations 1 Department of.


Hotcross bun sign in multiple system atrophy Eurorad

The 'hot cross bun' sign (HCBS) is a radiologic finding describing a cruciform T2 hyperintense signal on axial MRI of the pons.


hot cross bun sign The Scribble Doctor

The "hot cross bun" sign refers to pontine cruciform hyperintensity on long TR sequences, which can be observed in multiple-system atrophy, spinocerebellar atrophy types 2 and 3, 1 and in parkinsonism secondary to vasculitis. 2 It has not been previously demonstrated in variant Creutzfeldt-Jakob disease (vCJD), to our knowledge.


“Hot cross bun” sign in two patients with multiple system atrophycerebellar Neurology

The "hot cross bun" sign is a cruciform hyperintensity is seen on T2 weighted imaging within the pons. The sign is considered to be pathognomic for Multiple system atrophy type C. The clinical and radiological features of Multiple system atrophy type C overlap with the autosomal dominant inherited ataxias. We present a case series of 3.


MSA Hot Cross Bun sign

The hot cross bun sign is a characteristic MRI finding in cerebellar predominant multiple system atrophy, a rare neurodegenerative disorder. This article reviews the pathophysiology, clinical features, differential diagnosis, and prognosis of this condition, and provides illustrative cases and images.


Radiodiagnosis Imaging is AmazingInteresting cases Hot cross bun sign Multiple system atrophy

FIG. 1 (A) Figure demonstrating the hot cross bun sign in a patient with MSA‐C; (B) evolution of the etiologies associated with the hot cross bun sign. A majority of the new conditions associated with the HCB are rare and have been described only in a few case reports.